Proline has long been known to accumulate in plants experiencing water limitation and this has driven studies of proline as a beneficial solute allowing plants to increase cellular osmolarity during water limitation. Proline metabolism also has roles in redox buffering and energy transfer and is involved in plant pathogen interaction and programmed cell death. Some of these unique roles of prol...

The effect of various NaCl treatments (0, 50, 100, 200 and 300 mM) at different growth and development stages (tillering, boot swelling, flowering and polination) of two wheat cultivars (Ghods : salt-sensitive; Boolani : salt-resistant) on proline concentration and the kinetic activity of proline dehydrogenase was studied under greenhouse conditions. Generally, in response to salinity treatment...

PURPOSE OF REVIEW Proline metabolism impacts a number of regulatory targets in both animals and plants and is especially important in cancer. Glutamine, a related amino acid, is considered second in importance only to glucose as a substrate for tumors. But proline and glutamine are interconvertible and linked in their metabolism. In animals, proline and glutamine have specific regulatory functi...

Proline, an imino acid, has been well documented to be associated with the stress response induced by abiotic factors such as drought, cold and salinity in plants and biotic factors such as bacterial and fungal attacks. However, the regulatory mechanisms controlling proline metabolism, intercellular and intracellular transport and connections of proline to other metabolic pathways are poorly un...

SIGNIFICANCE The imino acid proline is utilized by different organisms to offset cellular imbalances caused by environmental stress. The wide use in nature of proline as a stress adaptor molecule indicates that proline has a fundamental biological role in stress response. Understanding the mechanisms by which proline enhances abiotic/biotic stress response will facilitate agricultural crop rese...